Anti-Apolipoprotein L1 ApoL1 Monoclonal Antibody

Product Name

Anti-Apolipoprotein L1 ApoL1 Monoclonal Antibody

View all Apolipoprotein L1 Antibodies

SKU/Catalog Number

M01841

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Apolipoprotein L1 ApoL1 Monoclonal Antibody catalog # M01841. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Apolipoprotein L1 ApoL1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01841)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

1D4

Isotype

IgG

Immunogen

Purified recombinant fragment of ApoL1 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01841 is reactive to APOL1 in Human

Applications

M01841 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

43.974kDa

Background of Apolipoprotein L1

Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:10000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Apolipoprotein L1 ApoL1 Monoclonal Antibody M01841

Western Blot (WB) analysis using ApoL1 Monoclonal Antibody against human plasma (1).
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For APOL1 (Source: Uniprot.org, NCBI)

Alternative Names

APOL; APO-L; APOL-I; Apolipoprotein L; apolipoprotein L, 1; apolipoprotein L1; Apolipoprotein L-I; FSGS4 APOL1 APO-L, APOL, APOL-I, FSGS4 apolipoprotein L1 apolipoprotein L1|apolipoprotein L 1|apolipoprotein L1-B3

For more info on APOL1, check out the APOL1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for APOL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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